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In turn, inactive MnSOD drives oxidative stress while promoting prooxidative proliferation and initiating a downstream effect on AKT activation, potentiating the survival of fibroid cells in a prooxidative environment [55]

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In the elderly, hypothyroidism is associated with accelerated cognitive decline and an increased risk of Alzheimer's disease, raising the possibility that impaired thyroid signaling may act as a modifiable risk factor for dementia (83)

The symptoms of epileptic seizures were assessed by a scoring system which is defined by Nissl Staining After anaesthetization with 10% (v/w) of chloral hydrate, the animals experienced transcardial perfusion with physical saline and 4% paraformaldehyde

Rats were placed in the water, and escape latencythe time (in seconds) taken to recognize the submerged platform in the designated quadrantwas measured